| 摘要 |
<p>HCH:CH; Y1=H, OH, CO2H, CN, acyloxy, optionally substituded CONH2; X=CH:CH, C:C; m=0-3; n=0-10; n'1-5; k=1-3) and their pharamaceutically acceptive salts were prepd. Thus, II was treated with 2, 6-dicarboxypyridine N-oxide and ceric ammonium nitrate to give 82% I(R,R1=MeO, R2=OH, X=C: C, m=o, n=4, q=3, k=1) which inhibited the prodn. of the slow-reacting substance of anaphyaxis(SRS-A) by 88% at 10μM compared with eicosatetryaynoic acid which inhibited SRS-A by 56.9% at 10μM in guinea prgs.</p> |
