| 摘要 |
<p>Compounds of formula (I), or a pharmaceutically acceptable salt and/or N-oxide and/or a solvate, wherein: one of X and Y is CO and the other is NH; E is O, S or NR wherein R is hydrogen, C1-6 alkyl or a protecting group and A is C2-4 alkylene or C2-4 alkenylene or E and A together with the phenyl to which they are attached form a quinoline nucleus; R4 is groups, (II), (III), (IV), wherein; p and q each independently are 0 to 2; Z is O or S; n is 0 or 1; having dopamine antagonist activity, a process for their preparation and their use as pharmaceuticals. </p> |
