发明名称 |
Pharmaceutical compositions for treating inflammation or arthritis. |
摘要 |
<p>The anti-inflammatory or anti-arthritic agent of this invention comprises a monometal complex of multivalent heavy metal and a polyfunctional organic ligand in a ratio of 1 : 1 of the metal to the ligand, the complex having a dissociation property represented by a sigmoidally shaped plot on a pM-pH diagram. Specific examples of the metal complex are dialkali metal monocopper (II) citrates represented by disodium-, dipotassium- or dilithium-monocopper (II) citrate. These dialkali monocopper (II) citrates have a dissociation property represented by a sigmoidal plot, wherein the curve of two directions meet at a point within the pH range of about 7 to about 9.</p> |
申请公布号 |
EP0115130(A1) |
申请公布日期 |
1984.08.08 |
申请号 |
EP19830307304 |
申请日期 |
1983.11.30 |
申请人 |
NATIONAL RESEARCH LABORATORIES |
发明人 |
MAURER, GERALD L. |
分类号 |
A61K31/28;A61K31/30;A61K31/315;A61P29/00;C07C59/235;C07C59/245;C07C59/255;C07C59/265;(IPC1-7):07C59/235;07C59/245;07C59/265;61K31/28;61K31/30;61K31/315 |
主分类号 |
A61K31/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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