摘要 |
A method of synthesizing L-serine from glycine and formaldehyde in the presence of biocatalytic amounts of serine hydroxymethyltransferase and tetrahydrofolate is disclosed. The serine hydroxymethyl- transferase may be amplified by cloning the gene therefor into a plasmid, and transforming a host cell, preferably Escherichia coli, Salmonella tymphimurium or Klebsiella aerogenes therewith. |