| 摘要 |
<p>A process for the preparation of new tricyclic pyrroles of the general formula I (I) wherein R1 denotes a hydrogen atom or an alkyl radical with 1 to 4 carbon atoms, R2 denotes a hydrogen atom, an alkyl radical with 1 to 4 carbon atoms or an alkenyl radical with 3 to 5 carbon atoms and R3 denotes an alkyl radical which has 1 to 4 carbon atoms and is-optionally substituted by a dialkylamino group with 1 to 4 carbon atoms in each alkyl radical, or denotes an alkenyl radical with 3 to 5 carbon atoms, or R2 and R3 together, with the inclusion of the nitrogen atom to which they are bonded, denote a pyrrolidino, piperidino, morpholino or perhydroazepino ring, a 1-piperazinyl radical which is optionally substituted in the 4-position by a methyl, ethyl or benzyl group, or a 1-homopiperazinyl radical which is optionally substituted in the 4-position by a methyl group, R4, R5 and R6 are identical or different and denote hydrogen or alkyl with 1 to 4 carbon atoms and n represents 1 or 2, and their acid addition salts is given. The compounds produced according to the invention have a protective action on the stomach and intestines and are suitable for the treatment of illnesses based on diseases of the stomach or intestine.</p> |
