发明名称 |
MERCAPTO ACYL-CARNITINES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME |
摘要 |
<p>"Mercapto acyl-carnitines, process for their preparation and pharmaceutical compositions containing same". s of the disclosures A novel class of mercapto acyl-carnitines is disclosed, wherein the mercapto acyl radical is the radical of saturated mercapto acids having from 2 to 10 carbon atoms. These mercapto acyl-carnitines are prepared e.g. by first preparing the corresponding halogen acyl-carnitine and then substituting therein, by nucleophylic substitution, the -SH group for the halogen atom. These mercapto acyl-carnitines are useful therapeutic agents, e.g. for the treatment of intoxications and burns and as mucolytic agents.</p> |
申请公布号 |
CA1168259(A) |
申请公布日期 |
1984.05.29 |
申请号 |
CA19820399576 |
申请日期 |
1982.03.26 |
申请人 |
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. |
发明人 |
TINTI, MARIA O.;QUARESIMA, EMMA T.;BAGOLINI, CARLO A.;DEWITT, PAOLO |
分类号 |
C07C323/52;A61K;A61K31/095;A61K31/195;A61K31/205;A61K31/21;A61K31/22;A61K31/23;A61K31/24;A61K31/255;A61K31/265;A61P3/02;A61P11/00;A61P43/00;C07C;C07C67/00;C07C233/45;C07C313/00;C07C319/14;(IPC1-7):C07C149/243 |
主分类号 |
C07C323/52 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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