发明名称 |
1,4;3,6 DIANHYDRO-2,5-DIAZIDO-2,5-DIDEOXY-HEXITOLS |
摘要 |
<p>The invention relates to new stereoisomeric 1,4;3,6-dianhydro-2,5-diazido-2,5-dideoxy-hexitols of the Formula I. these compounds can be prepared by a/ reacting a hexitol derivative of the general Formula II /wherein R is a mesyl or tosyl group/ in an aqueous or anhydrous organic solvent with an alkali metal azide or ammonium azide; or b/ mesylating or tosylating a compound of the Formula III and treating the mixed ester of the general Formula IV thus obtained /wherein R is as stated above/ with a base; or c/ subjecting a compound of the Formula III to debenzoylation and subsequently to partial esterification and treating the compound of the general Formula V thus obtained /wherein R is as stated above/ with a base. The new compounds of the Formula I possess valuble hypnotic properties and can be used in therapy.</p> |
申请公布号 |
CA1166647(A) |
申请公布日期 |
1984.05.01 |
申请号 |
CA19810373268 |
申请日期 |
1981.03.18 |
申请人 |
EGYT GYOGYSZERVEGYESZETI GYAR |
发明人 |
KUSZMANN, JANOS;MEDGYES, GABOR;ANDRASY, FERENC;BERZSENYI, PAL |
分类号 |
C07D493/04;(IPC1-7):C07D493/04 |
主分类号 |
C07D493/04 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|