发明名称 |
Method of synthesis of 1-dodecylazacycloheptan-2-one |
摘要 |
In a method of synthesis of 1-substituted azacycloalkan-2-ones with primary alkyl halides and aralkyl halides as alkylating agents, the improvement comprising carrying out the N-alkylation in the presence of a phase transfer catalyst having the structural formula <IMAGE> where X is suitable anion; and R1, R2, R3 and R4 are each alkyl or aralkyl groups having 1-18 carbon atoms, or R2, R3 and R4 can form a part of a heterocyclic ring, with the proviso that the combined total of carbon atoms is between 16 and 40.
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申请公布号 |
US4422970(A) |
申请公布日期 |
1983.12.27 |
申请号 |
US19820380162 |
申请日期 |
1982.05.20 |
申请人 |
NELSON RESEARCH & DEVELOPMENT COMPANY |
发明人 |
RAJADHYAKSHA, VITHAL J.;PECK, JAMES V.;MINASKANIAN, GEVORK |
分类号 |
C07B61/00;C07D223/10;C07D225/02;C07D227/087;(IPC1-7):C07D223/10 |
主分类号 |
C07B61/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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