| 摘要 |
1. A pharmaceutical composition suitable for parenteral administration having anti-inflammatory and analgesic property and being prepared and kept in a gas-inert atmosphere, characterized by the fact that it contains a 2-arylpropionic acid selected from the group consisting of ketoprofen, ibuprofen, naproxen, tiaprofenic acid, with a base selected from α-amino acid, droproizine and tromethamine in racemic as well as in enantiomeric form, in an aqueous solution having an osmolarity between 270 and 310 mOsrm/kg and at a pH in the range between 7.0 and 7.5, said solution being free of preservatives and of supporting substances. 2. A pharmaceutical composition according to Claim 1, characterized by the fact that the alkylammonium salt of the 2-arylpropionic acid is the d, 1-lysine salt of (R, S)-ketoproten and the inert gas is nitrogen. 3. A pharmaceutical composition according to Claim 1, characterized by the fact that the alkylanononium salt of the 2-arylpropionic acid is the 1-lysine salt of (R, S) -ketoprofen. 4. A pharmaceutical composition according to Claim 1, characterized by the fact that the alkylammonium salt of the 2-arylpropionic acid is the 1-lysine salt of R-ketoprofen. 5. A pharmaceutical composition according to Claim 1, characterized by the fact that the alkylanroonium salt of the 2-arylpropionic acid is the 1-dropropizine salt of R-ketoprofen. 6. A pharmaceutical composition according to Claim 1, characterized by the fact that the alkylancnoniuro salt of the 2-arylpropionic acid is the tromethamine salt of S-ketoprofen. 7. A pharmaceutical composition according to Claim 1, characterized by the fact that the alkylancnoniuro salt of the 2-arylpropionic acid is the tromethamine salt of R-ketoprofen. 8. A pharmaceutical composition according to Claim 1, characterized by the fact that the alkylancnonium salt of the 2-arylpropionic acid is the 1-lysine salt of S-ketoprofen. 9. Process for the preparation of the pharmaceutical composition according to Claim 1, characterized by that an alkylamrnonium salt of a 2-arylpropionic acid selected from the group consisting of ketoprofen, ibuprofen, naproxen and tiaprofenic acid with a base selected from α-amino acid, droproizine and tromethamine suitably dissolved in water for injectable preparation at a pH between 7.0 and 7.5 in an atmosphere of an inert gas and away from light. |
