发明名称 Oxadiazolopyrimidine derivatives
摘要 Oxadiazolo[2,3-c]pyrimidine derivatives of the formula <IMAGE> I wherein R is alkyl, alkenyl, alkynyl or alkoxyalkyl, as well as their salts, are described. The compounds of formula I have valuable, long-lasting vasodilating and/or blood pressure-lowering properties and are useful for the treatment of vascular-conditioned hypertensions or as vasodilators in peripheral blood supply disorders. The compounds are prepared, inter alia, by carbamoylating the corresponding derivative containing a free amino group and optional salt formation.
申请公布号 US4410698(A) 申请公布日期 1983.10.18
申请号 US19820407870 申请日期 1982.08.13
申请人 HOFFMANN-LA ROCHE INC. 发明人 HENGARTNER, URS;MULLER, JEAN-CLAUDE;RAMUZ, HENRI
分类号 A61K31/505;C07D235/06;C07D498/04;C07D521/00;(IPC1-7):C07D498/22;A61K31/50 主分类号 A61K31/505
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