发明名称 Cardiotonic 4-aroylimidazolidin-2-ones
摘要 This invention relates to aroyl-2-imidazolidinones of the following general structure which are useful as cardiotonics and antihypertensive agents <IMAGE> wherein Ar is furanyl, thienyl, 1H-pyrrolyl, or phenyl optionally substituted with one or two X groups; X is halogen, hydroxy, lower alkyl, lower alkoxy, lower alkylthio, lower alkylsulfoxide, lower alkylsulphone, trifluoromethyl, -SO2N(R2)2, NR3R4, pyrrolidino, piperidino, morpholino, piperazino or N'-alkyl-piperazino; R is hydrogen, lower alkyl, lower alkylcarbonyl or benzoyl; each of R1, R2, R3 and R4 is hydrogen or lower alkyl; T is an oxygen atom or a divalent sulfur atom; and the pharmaceutically acceptable salts thereof.
申请公布号 US4410540(A) 申请公布日期 1983.10.18
申请号 US19810317963 申请日期 1981.11.04
申请人 MERRELL DOW PHARMACEUTICALS INC. 发明人 SCHNETTLER, RICHARD A.;DAGE, RICHARD C.;GRISAR, J. MARTIN
分类号 C07D233/34;A61K31/415;A61K31/4166;A61K31/443;A61K31/445;A61P9/04;A61P9/12;A61P25/02;C07D233/32;C07D233/38;C07D403/06;C07D405/06;C07D409/06;(IPC1-7):A61K31/41 主分类号 C07D233/34
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