| 摘要 |
<p>Process comprises pptn. of cpd. of formula (I). To increase efficiency, condensn. of h-picoline with DMF in the presence of phosphoryl chloride, gives 3-(N,N-dimethylamino) 2-(4-pyridinyl)acrolein, for Micheal reaction with nitroacetamide and cyclisation to yield 3-nitro-5-(4-pyridinyl) 2-(1H)-pyridinone. - This latter, treated with powdered iron and hydrochloric acid in methanol, produces 3-amino-5-(4-pyridinyl) 2-</p> |
