| 发明名称 |
Semi-synthesis of human insulin |
| 摘要 |
A process for preparing B30-threonine-insulin which comprising reacting a des-B30-insulin with an excess amount of threonine derivative in the presence of an enzyme specifically acting on a lysine carbonyl in peptide bondings and produced by Achromobacter lyticus M 497-1.
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| 申请公布号 |
US4401757(A) |
申请公布日期 |
1983.08.30 |
| 申请号 |
US19810336072 |
申请日期 |
1981.12.31 |
| 申请人 |
SHIONOGI & CO., LTD. |
发明人 |
MORIHARA, KAZUYUKI;OKA, TATSUSHI;SOEJIMA, MASAMI;MASAKI, TAKEHARU |
| 分类号 |
C12P21/00;C07K14/62;C12P21/02;C12P21/04;(IPC1-7):C12P21/04;C12R1/02 |
主分类号 |
C12P21/00 |
| 代理机构 |
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代理人 |
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| 主权项 |
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