发明名称 |
ARZNEIMITTEL, DARIN ENTHALTENE VICINALE DIHYDROXYALKYLXANTHINE UND HERSTELLUNGSVERFAHREN FUER DIESE XANTHINVERBINDUNGEN |
摘要 |
Compounds of the formula <IMAGE> (I) wherein one of the radicals R1, R2 or R3 denotes a straight-chain alkyl group having 4 to 8 C atoms and two vicinal hydroxyl groups in the omega , omega -1 or omega -1, omega -2 positions and the two other radicals represent straight-chain or branched alkyl groups having up to 12 C atoms in the position of R1 and R3 and up to 4 C atoms in the position of R2, the total of C atoms in these two alkyl substituents being a maximum of 14, are prepared by oxidation of the corresponding alkenylxanthines and by alkylation with compounds which introduce the dihydroxyalkyl radical or a precursor thereof. The dihydroxyalkyldialkylxanthines are suitable for the treatment of obstructive respiratory tract diseases. |
申请公布号 |
DE3138397(A1) |
申请公布日期 |
1983.04.07 |
申请号 |
DE19813138397 |
申请日期 |
1981.09.26 |
申请人 |
HOECHST AG |
发明人 |
FURRER,HARALD,DR.;ANAGNOSTOPULOS,HIRISTO;GEBERT,ULRICH,DR.;HINZE,HEINZ-JOACHIM,DR. |
分类号 |
A61K31/52;A61K31/522;A61P11/08;C07C21/04;C07C29/10;C07C31/42;C07D303/08;C07D317/16;C07D317/20;C07D473/06;C07D473/08;C07D473/10 |
主分类号 |
A61K31/52 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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