| 摘要 |
<p>A pharmaceutical preparation containing as active ingredient a compound of the formula
<Chemistry id="chema01" num="0001"><Image id="ia01" he="40" wi="90" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>or a therapeutically acceptable salt thereof in which formula
<UnorderedLists id="ula01" listStyle="none"><ListItem>R' and R<Sup>2</Sup> are the same or different and each selected from the group consisting of H. CF<Sub>3</Sub>, NO<Sub>2</Sub>, -COOCH<Sub>3</Sub>, -COOC<Sub>2</Sub>H<Sub>5</Sub>, alkyl containing 1-7 carbon atoms, halogen, alkoxy, containing 1-5 carbon atoms, and alkanoyl containing 1-4 carbon atoms.</ListItem><ListItem>R is selected from the group consisting of H, alkanoyl <!-- EPO <DP n="2"> -->containing 1-4 carbon atoms, and carboalkoxycontaining 2-6 carbon atoms;</ListItem><ListItem>and R<Sup>3</Sup>, R<Sup>4</Sup> and R<Sup>5</Sup>, which are the same or different, are each selected from the group consisting of H, CH<Sub>3</Sub>, C<Sub>2</Sub>H<Sub>s</Sub>, OCH<Sub>3</Sub>, OC<Sub>2</Sub>H<Sub>5</Sub>, OCH<Sub>2</Sub>CH<Sub>2</Sub>OCH<Sub>3</Sub>, and OCH<Sub>2</Sub>CH<Sub>2</Sub>OCH<Sub>2</Sub>CH<Sub>3</Sub>: provided that
<UnorderedLists id="ula02" listStyle="none"><ListItem>a) at least one of R<Sup>3</Sup>, R<Sup>4</Sup> and R<Sup>5</Sup> is selected from the group consisting of CH<Sub>3</Sub>, C<Sub>2</Sub>H<Sub>5</Sub>, OCH<Sub>3</Sub>, OC<Sub>2</Sub>H<Sub>5</Sub>, OCH<Sub>2</Sub>CH<Sub>2</Sub>OCH<Sub>3</Sub>, and OCH<Sub>2</Sub>CH<Sub>2</Sub>OCH<Sub>2</Sub>CH<Sub>3</Sub>, and</ListItem><ListItem>b) when two of R<Sup>3</Sup>, R<Sup>4</Sup> and R<Sup>5</Sup> are H, then the remaining radical R<Sup>3</Sup>, R<Sup>4</Sup> or R<Sup>5</Sup> is selected from the group consisting of OCH<Sub>3</Sub>, OC<Sub>2</Sub>H<Sub>5</Sub>, OCH<Sub>2</Sub>CH<Sub>2</Sub>OCH<Sub>3</Sub>. and OCH<Sub>2</Sub>CH<Sub>2</Sub>OCH<Sub>2</Sub>CH<Sub>3</Sub>; the use of the compounds for inhibiting gastric acid secretion; compounds included in the formula 1, and processes for their preparation.</ListItem></UnorderedLists></ListItem></UnorderedLists></p> |
