ANVENDNING AV BIOLOGISKT AKTIVA FORENINGAR BESTAENDE AV EN BIOLOGISKT AKTIVSUBSTANS BUNDEN TILL EN HYDROFIL BERARPOLYMER, SOM UTGORES AV POLYHYDROXIMETYLEN, FOR AFFINITETSKROMATOGRAFERING, UTVINNING AV ANTIKROPPAR ELLER

摘要

The biologically active substance is bound covalently to poly(hydroxymethylene) or poly(vinylenecarbonate) either directly or after reaction with a coupling component. The coupling component, which is optionally employed, is bound to the poly(hydroxymethylene) and the biologically active compound by a covalent bond in each case. When poly(vinylenecarbonate) is used, the remaining carbonate groups are hydrolysed. The biologically active substances which are obtained are suitable for use in affinity chromatography.