摘要 |
New 1,5-diphenylpyrazolin-3-one compounds and a method of preparing them are described. The compounds have the general formula I <IMAGE> I where R1 is a hydrogen or halogen atom, or a lower alkyl, lower alkoxy, hydroxy, trifluoromethyl or lower alkanoyloxy radical, R2 is a hydrogen or halogen atom, or a lower alkyl, or lower alkoxy radical, or R1 and R2 are bonded to adjacent carbon atoms and together denote a methylenedioxy or ethylenedioxy radical, R3 is a hydrogen or halogen atom, or a lower alkyl, lower alkoxy, hydroxy, trifluoromethyl or lower alkanoyloxy radical, R4 is a hydrogen or halogen atom, or a lower alkyl, lower alkoxy radical, or R3 and R4 are bonded to adjacent carbon atoms and together denote a methylenedioxy or ethylenedioxy radical, Z is an alkylene radical with 2 to 6 carbon atoms and R5 is an optionally substituted pyridyl radical, a thienyl radical or an optionally substituted phenyl radical. The compounds have pharmacological properties, for example antiallergic properties. |