| 摘要 |
<p>PURPOSE:To provide a specific L-proline-producing strain having specific properties. CONSTITUTION:A variant belonging to Brevibacterium genus, Corynebacterium genus, or Microbacterium genus, resistant to DL-3,4-dehydroproline, and capable of producing L-proline, e.g. Brevibacterium lactofermentum, Brevibacterium flavum, Corynebacterium glutamicum, Microbacterium ammoniaphilum, etc. L- proline is produced by culturing the bacteria in a conventional medium at 20-40 deg.C and pH4-10 for 20-100 hours. The above variant can be obtained, e.g. by treating L-proline-producing Corynebacterium, etc. with N-methyl-N-nitro-N'-nitrosoguanidine.</p> |
