发明名称 |
NOVEL AMIDINE COMPOUNDS, PROCESS FOR PRODUCING SAME AND ANTI-COMPLEMENT AGENT COMPRISING THEM |
摘要 |
<p>Amidino compounds represented by the formula <IMAGE> and pharmaceutically acceptable acid addition salts thereof are novel compounds and are useful as powerful antitrypsine, antiplasmin, antikallikrein and antithrombin agents. Having strong anti-C1 (C1 &upbar& r, C1 &upbar& s) activities and an anticomplement activity, they are also useful as anticomplement agents. These amidino compounds are prepared by usual esterification of carboxylic acid compounds represented by the formula <IMAGE> with 6-amidino-2-naphthol and, if necessary, can be transformed into pharmaceuticlly acceptable acid addition salts thereof.</p> |
申请公布号 |
EP0048433(A3) |
申请公布日期 |
1982.07.21 |
申请号 |
EP19810107274 |
申请日期 |
1981.09.15 |
申请人 |
TORII & CO., LTD. |
发明人 |
OKUTOME, TOSHIYUKI;NAKAYAMA, TOYOO;YAEGASHI, TAKASHI;KURUMI, MASATERU;FUJII, SETSURO |
分类号 |
C07C249/02;A61K31/155;C07C257/18;C07C279/18;C07D317/68;(IPC1-7):07C123/00;61K31/155;07C129/08 |
主分类号 |
C07C249/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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