Method for the preparation of a sodium salt of 1-alkyne compound

摘要

The invention provides a novel and improved method for the preparation of a sodium salt of a 1-alkyne of the general formula <IMAGE> in which R1 and R2 are each a hydrogen atom or a monovalent hydrocarbon group free from aliphatic unsaturation, by the reaction of a corresponding 1,2-alkadiene with metallic sodium in an inert organic solvent. According to the invention, the metallic sodium is dispersed in the inert solvent as finely as possible to have a particle diameter not exceeding 1000 mu m so as that the reaction velocity is very much increased even under atmospheric pressure to give an improved yield of the product.