| 摘要 |
The invention relates to novel anticarcinogenic compounds of formula I, <IMAGE> (I) wherein R1 is halogen R2 is hydroxy or R1 and R2 together form an oxygen bridge, R3 is methyl, R4 is hydrogen, methyl or acyl, n is 1 or zero, with the provisos, that in case n is 1 the steric positions of -R2, OR3 and -OR4 groups correspond to dulcitol, mannitol or sorbitol configurations independently of their actual meanings, in case n is zero the steric positions of -R2 and -OR3 groups correspond to xylitol configuration independently of their actual meanings. The novel compounds can be used as antitumor agents in themselves or formulated as pharmaceutical preparations.
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