发明名称 Oxadiazolotriazine derivatives
摘要 Oxadiazolotriazine derivatives of the formula <IMAGE> I wherein R1, R2 and R3 are as hereinafter set forth, are described. A process for preparing compounds of formula I wherein R1 is hydrogen, R2 is a group of the formula -COOR5, wherein R5 is as hereinafter set forth, and R3 is as hereinafter set forth, by cyclizing an intermediate of the formula <IMAGE> IV wherein R3 and R5 are as hereinafter set forth, is also described. The compounds of formula I are useful in the treatment of vascular-condition hypertension or also as vasodilators in the case of peripheral blood supply disorders.
申请公布号 US4336380(A) 申请公布日期 1982.06.22
申请号 US19810234538 申请日期 1981.02.17
申请人 HOFFMANN-LA ROCHE INC. 发明人 MULLER, JEAN-CLAUDE;RAMUZ, HENRI
分类号 C07D211/98;C07D251/66;C07D498/04;(IPC1-7):C07D251/66 主分类号 C07D211/98
代理机构 代理人
主权项
地址