PROCESS FOR PRODUCING DETOXIFIED PHARMACEUTICAL PRODUCTS CONTAINING A CYTOSTATICALLY ACTIVE ALKYLATING AGENT

摘要

The present invention is related to a process for producing a pharmaceutical preparation containing a cytostatically active alkylating agent which has been detoxified by adding thereto a a pharmacologically acceptable salt of a mercapto alkane sulfonic acid of the general formula HS-alk-SO3H wherein alk is an alkylene group having from 2 to 6 carbon atoms, in an amount of at least 20 % of the weight of the alkylating agent thereby substantially improving the properties thereof.