ORAL PREPARATION FOR RELEASE IN LOWER DIGESTIVE TRACTS

摘要

An oral preparation for release in lower digestive tracts, prepared by filling a hard capsule made from a base mainly comprising chitosan with a solid preparation containing a principal agent and a solid organic acid which, in a dissolved state, can dissolve chitosan and forming an enteric coating on the surface of the capsule. The preparation enables any desired release time to be set without being affected by the pH by virtue of the water-permeability due to the porousness of the chitosan.