| 摘要 |
<p>D-HOMO OXASTEROIDS Novel steroids, which can be used as antiinflammatory agents, have the formula or the 1,2-dehydro derivative thereof; wherein R1 is hydrogen, alkyl-?-O-, aryl-?-0-, halogen or hydroxy; R2 is hydrogen or alkyl; R3 is alkyl; R4 is carbonyl, .beta.-hydroxymethylene, .beta.-chloromethylene or .beta.-bromomethyl-ene; R5 is hydrogen, fluorine, chlorine or bromine; R6 is hydrogen, fluorine or methyl; and R7 is hydrogen, chlorine or bromine; with the proviso that when R1 is hydroxy, R2 is alkyl; and with the further proviso that when R2 is alkyl, it is the same alkyl group as R3; wherein aryl is phenyl or phenyl substituted with one or two alkyl, alkoxy or halogen groups; and alkyl and alkoxy are groups having 1 to 10 carbon atoms.</p> |
