发明名称 C5AR ANTAGONISTS
摘要 PROBLEM TO BE SOLVED: To provide compounds that are modulators of the C5a receptor, and pharmaceutical compositions, comprising at least one of the compounds.SOLUTION: Compounds are provided that are modulators of the C5a receptor, where the compounds are substituted piperidines. There are also provided pharmaceutical compositions, comprising at least one of the compounds, for the treatment of diseases and disorders associated with the activation of C5a receptors.SELECTED DRAWING: Figure 1X
申请公布号 JP2016130249(A) 申请公布日期 2016.07.21
申请号 JP20160053725 申请日期 2016.03.17
申请人 CHEMOCENTRYX INC 发明人 FAN PINGCHEN;KEVIN LLOYD GREENMAN;MANMOHAN REDDY LELETI;LI YANDONG;JAY POWERS;TANAKA HIROKO;YANG JU;ZENG YIBIN
分类号 C07D211/60;A61K31/445;A61K31/451;A61K31/4525;A61K31/453;A61K31/454;A61K31/4545;A61K31/5377;A61P1/04;A61P1/18;A61P3/10;A61P3/12;A61P7/00;A61P7/02;A61P7/04;A61P9/00;A61P9/08;A61P9/10;A61P11/00;A61P11/06;A61P13/12;A61P17/00;A61P17/02;A61P17/04;A61P17/06;A61P19/02;A61P21/00;A61P21/04;A61P25/00;A61P25/28;A61P27/00;A61P29/00;A61P31/04;A61P35/00;A61P37/02;A61P37/06;A61P37/08;A61P43/00;C07D401/04;C07D401/10;C07D401/12;C07D401/14;C07D405/12;C07D413/10;C07D413/12 主分类号 C07D211/60
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