Anti-ulcer treatment method

摘要

A method for treating ulcers or hypersecretion is described employing an anti-ulcer agent of formula I. Accordingly the invention provides a method for treating ulcers or hypersecretion in a mammal which comprises administering to said mammal an effective amount of an anti-ulcer agent of formula I (I) wherein R is alkyl of 1 to 6 carbon atoms or aralkyl of 7 to 12 carbon atoms, R1 is hydrogen or alkyl of 1 to 6 carbon atoms, Z- is an anion selected from halide, lower alkyl- and arylsulphonate and the R and R1 radicals may be the same or different, and A represents a methylene or ethylene radical optionally substituted by alkyl of 1 to 6 carbon atoms, oxo or hydroxy and S is sulphur. Anti-ulcer compositions comprising a compound of formula I and a pharmaceutical carrier are also described.