| 摘要 |
PURPOSE:To prepare the titled compound useful as a raw material of bioactive substances such as pesticides, pharmaceuticals, etc., economically, in an industrial scale, by the direct halogenation of acrylonitrile in the presence of an alkali or alkaline earth metal carbonate or bicarbonate, in the dark. CONSTITUTION:The objective 2,3-dihalogenopropionitrile can be prepared by halogenating acrylonitrile directly with a halogenating agent such as bromine, chlorine, etc. in the presence of a catalytic amount of the carbonate or bicarbonate of an alkali or alkaline earth metal (e.g. sodium carbonate, potassium bicarbonate, etc.) under dary conditions, pref. in the absence of oxygen, i.e. in an inert gas atmosphere. The reaction is pref. carried out in an apparatus lined with glass, etc. under essentially anhydrous conditions. |
