| 摘要 |
Substituted piperazinyliminorifamycins having the following structural formula: <IMAGE> wherein Me represents a methyl group and Z represents alkenyl of 3 to 5 carbon atoms, alkynyl of 3 to 5 carbon atoms, 5- or 7-membered cycloalkenyl, cycloalkyl-(C1-C2) alkyl wherein the cycloalkyl moiety is a 3- or 7-membered ring or cycloalkenyl-(C1-C2)alkyl wherein the cycloalkenyl moiety is a 5- or 7-membered ring. The compounds have a broad spectrum antibacterial utility accompanied by a low toxicity. |
