发明名称 GENE VETTORE RICOMBINANTE CELLULA ELORO PROCEDIMENTI DI PRODUZIONE PER PREPARARE UNA PROTEINA ASSOMIGLIANTE AD INTERFERONE UMANO
摘要 A game for expressing a protein (A) having properties close to those of human interferon, consists of a coding chain and a complementary chain in which the coding chain comprises a specified sequence of 290 codons (289 triplets plus a 3'-terminal CA pair), or a sub-unit or equiv. of this sequence. Also new is a plasmid recombinant consisting of a rector into which such a gene has been inserted, there being upstream of, and adjacent to, the inserted gene a bacterial promotor which controls the gene. Cells, modified by these plasmids and method for producing (A) by cultivation of such cells are also claimed. (A) have antiviral activity.
申请公布号 IT8147715(D0) 申请公布日期 1981.02.04
申请号 IT19810047715 申请日期 1981.02.04
申请人 G.D.SEARLE & CO. 发明人 HOUGHTON MICHAEL;STEWART ANDREW GEORGE;CAREY NORMAN HENRY;EATON MICHAEL ANTHONY WILLIAM
分类号 C07K14/565;C12N15/00 主分类号 C07K14/565
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