发明名称 |
2-Alkynyl-5-indanyloxyacetic acids |
摘要 |
Indanyloxy compounds having 2-alkynyl substituents which exhibit diuretic, saluretic, and uricosuric activity are described. The compounds are obtained according to a process involving selective etherification of a 5-hydroxyindanone followed by alkynylation with a silylated alkynyl bromide to provide novel silylated intermediates which are hydrolyzed to indanyloxy compounds such as (6,7-dichloro-1-oxo-2-phenyl-2-propargyl-5-indanyloxy)acetic acid.
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申请公布号 |
US4247715(A) |
申请公布日期 |
1981.01.27 |
申请号 |
US19790027961 |
申请日期 |
1979.04.09 |
申请人 |
MEAD JOHNSON & COMPANY |
发明人 |
JOHNSON, PORTER C.;MATIER, WILLIAM L. |
分类号 |
C07C45/46;C07C45/67;C07C45/68;C07C49/84;C07C62/38;(IPC1-7):C07C59/90 |
主分类号 |
C07C45/46 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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