| 摘要 |
The invention relates to new products, in the form of bases or salts, derivatives of hexahydro-6-canthinone which may be substituted and are represented by the general formula: <IMAGE> (I) in which R1 represents a hydrogen atom or hydroxy, C1-C5 alkyl, C2-C5 acyloxy, methoxy or halo radical and R2 represents a hydrogen atom or straight or branched C1-C5 alkyl radical with the proviso that R1 is not hydrogen or hydroxy in the 8-position when R2 is methyl or R1 is not methoxy in the 10-position when R2 is hydrogen. The new products are especially useful for treating cardio-circulatory, cerebro-vascular and respiratory insufficiencies. The invention also relates to a process in which the hexahydro-6-canthinone compounds are obtained by treating a Nb-alkyltryptamine with beta -formylpropionic acid in an aromatic hydrocarbon at the reflux temperature of the reaction medium.
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