发明名称 66METHOXYY22ACETYLNAPHTHALENEOXIME DERIVATIVE*ITS MANUFACTURE AND MEDICAL COMPOSITION
摘要 The invention concerns 6-methoxy-2-acetylnaphthalene oxime derivatives of the general formula <IMAGE> in which R1 and R2 each represent a lower alkyl radical, or form, in association with the nitrogen atom to which they are linked, a saturated heterocyclic group, and the acid addition salts thereof with physiologically acceptable acids. These derivatives have analgesic, antipyretic and anti-inflammatory activity and can be made up into pharmaceutical compositions in tablet, capsule, suppository and the like forms. The derivatives of the invention may be prepared by reacting the corresponding 2-acetyl-6-methoxynaphthalene oximes with an appropriate substituted halogeno-ethylamine.
申请公布号 JPS5555155(A) 申请公布日期 1980.04.22
申请号 JP19790098600 申请日期 1979.08.01
申请人 PROVESAN SA 发明人 ANTONIO ESUTEEBU SUBIRANA
分类号 C07D295/08;A61K31/15;A61K31/395;A61P25/04;A61P29/00;B01D17/00;C07C67/00;C07C239/00;C07C249/12;C07C251/54;C07C251/58;C07D295/088 主分类号 C07D295/08
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