摘要 |
Long chain fatty acid amides of styryl hexahydroindolinols in which the amido portions have ethyleneically unsaturated positions or cyclopropanyl rings, eg 1-(1-oxo-9-cis-octadecenyl)-(3aRS, 4RS, 7aRS)-4-(Z)-(3,4-dimethoxy)-styryl-hexahydro-4-indolinol, are useful as cholesterol ester-reducing agents and are obtainable by reacting corresponding long chain carboxylic acids (or derivatives thereof) with appropriate 4-styryl-4-hexahydroindolinols.
|