发明名称 Cholesterol ester-reducing amides of hexahydroindolinols
摘要 Long chain fatty acid amides of styryl hexahydroindolinols in which the amido portions have ethyleneically unsaturated positions or cyclopropanyl rings, eg 1-(1-oxo-9-cis-octadecenyl)-(3aRS, 4RS, 7aRS)-4-(Z)-(3,4-dimethoxy)-styryl-hexahydro-4-indolinol, are useful as cholesterol ester-reducing agents and are obtainable by reacting corresponding long chain carboxylic acids (or derivatives thereof) with appropriate 4-styryl-4-hexahydroindolinols.
申请公布号 US4194002(A) 申请公布日期 1980.03.18
申请号 US19780891298 申请日期 1978.03.29
申请人 SANDOZ INC 发明人 KATHAWALA, FAIZULLA G
分类号 A61K31/40;C07D209/04;C07D209/08;(IPC1-7):A61K31/40 主分类号 A61K31/40
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