Removable drug implant

摘要

There is disclosed an implant which has an inert, biocompatible core with a coating comprising from about 5 to about 40% of estradiol in a biocompatible dimethylpolysiloxane rubber. When the implant is placed under the skin of a ruminant animal the estradiol is released at a substantially constant rate to produce a greater than normal weight gain in the animal. The implant remains intact and may be removed from the animal at the end of the desired period of drug administration.