摘要 |
<p>The present invention encompasses a method for determining a class specific antibody to an antigen comprising: (a) binding an antibody for a specific immunoglobulin class to a solid support to form a class specific antibody reagent; (b) reacting the class specific antibody reagent with test sample; (c) removing unbound test sample to provide an antigen reagent, and (d) reacting the antigen reagent with a known antigen and measuring the amount of bound antigen thereby determining the amount of class specific antibody to that antigen. The present invention is useful for differential diagnosis, since the relative amount of class specific antibodies varies with the progress of infection.</p> |