| 摘要 |
Bactericidal 4,6-di-(aminoglycocyl)-1,3- diaminocyclitol I (gentamicin A, B, B1, C1-C1a, C2, C2a, X2, sisomicin, verdamicin, antibiotics G-418, 66-40B, 66-40D, JI-20A, Ji-20B and G-52), which lposition of I was substituted by X (X = S-3-amino-2-hydroxypropionyl, S-4-amino-2-hydroxybutyl), and their pharmaceutical nontoxic acid additives were prepd. by the reaction of 4,6-di-(aminoglycyl)-1,3-diaminocyclitol and HO-X1-X1 = amino and/or hydroxy group protected at X).
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