Alpha olefin isomerization in preparing alkane phosphonic acids and intermediates

摘要

Preparation of long chain alkane phosphonic acids involves reacting alpha olefin with macroreticular strong acid cation exchange resin to isomerize the olefin, reacting resulting internally unsaturated olefin with dimethylphosphite to produce non-terminally substituted alkanephosphonic acid dimethyl ester, and demethylating with anhydrous hydrogen chloride or hydrogen bromide.