发明名称 VERFAHREN ZUR HERSTELLUNG VON 5-SUBSTITUIERTEN 1,2-DIHYDRO-3H-PYRROLO ECKIGE KLAMMER AUF 1,2-A ECKIGE KLAMMER ZU PYRROL-1-CARBONSAEUREN
摘要 <p>Compounds of the formula: …<CHEM>… wherein Y is …<CHEM>… in which R is hydrogen, methyl, chloro or bromo, the R substitution being at the 3, 4 or 5 positions of the thiophene ring,… R<1> is hydrogen, a lower alkyl group having 1 to 4 carbon atoms, a lower alkoxy group having from 1 to 4 carbon atoms, chloro, fluoro or bromo, the R<1> substitution being at the ortho, meta or para positions of the aroyl group, and… R<2> is hydrogen or a lower alkyl group having from 1 to 4 carbon atoms. …<??>These compounds are used as intermediates for the preparation of the corresponding 1-carboxylic acid compounds by hydrolysis, the latter compounds being pharmaceutically useful.</p>
申请公布号 DD137229(A5) 申请公布日期 1979.08.22
申请号 DD19780206857 申请日期 1978.07.21
申请人 SYNTEX(USA)INC,US 发明人 VAN HORN,ALBERT R.,US;GALLEGRA,PASQUALE G.,US
分类号 A61K31/40;A61P25/04;A61P29/00;C07D207/32;C07D207/335;C07D207/337;C07D333/38;C07D487/04;(IPC1-7):C07D403/06 主分类号 A61K31/40
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