PROCESS FOR THE PREPARING OF 2,4-DIOSO-3,3-DIETHYL-TETRAHYDRO PYRIDINE

摘要

Title compd. (I) useful as analgesic(no data) was prepd. by condensation of H2N-CH=CHCO-C(C2H5)2-COOR(II) Thus, II reacted in a three necked flask at 250≦̸C under atmospheric pressure for 2-3hr followed by distillation at 175-190≦̸C and 9mmHg gave yellow liquid of I. The decoloration crystal from the yellow liquid was proceeded by 100ml ethanol to give 117.6g pure I.