发明名称 Preparation of fibrous collagen product having hemostatic and wound sealing properties
摘要 A fluffy, finely-divided fibrous collagen derived product having hemostatic and adhesive properties sufficient to join together severed biological surfaces in a live warm blooded animal when the product is wet with blood between the surfaces. In the preparation of the product, water-wet collagen is treated with ethanol to remove water, is converted to a ionizable partial salt in the presence of ethanol and dehydrated with ethanol so as to control and limit the swelling of the collagen fibers and prevent hornification upon drying. The recovered dry material is subjected to deaggregation to form a mass having a bulk density of not more than 8 pounds per cubic foot and a surface area of at least 1 square meter per gram.
申请公布号 US4148664(A) 申请公布日期 1979.04.10
申请号 US19780897502 申请日期 1978.04.18
申请人 AVICON, INC. 发明人 CRUZ, JR., MAMERTO M.
分类号 A61L15/32;(IPC1-7):C08L89/00;C09H1/00 主分类号 A61L15/32
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