| 摘要 |
A compound of the formula (I): <IMAGE> (I) wherein A is a monocyclic or polycyclic heteroaromatic ring containing at least one nitrogen atom as a hetero atom, which may be unsubstituted or substituted with one or more substituents; R is a phenyl group which can be unsubstituted or substituted or a thienyl group; T is (1) a -CH2-S-Het group, where Het is a tetrazolopyridazine ring, a triazolopyridazine ring, or a triazolopyridine ring, (2) <IMAGE> WHERE R1 and R2, which may be the same or different, each is a hydrogen atom or a (C1-C4)alkyl group, (3) a -CH2N3 group or (4) a -CH2S-D group in which D is a group selected from the group consisting of <IMAGE> <IMAGE> +tr <IMAGE> where m and n each is 0 to 3; with the proviso that (A) WHEN T is the -CH2SD group wherein D is as defined above then the HO-A- moiety is a <IMAGE> where B represents the non-metallic atoms necessary to complete a pyridine ring, a pyrimidine ring or a pyrazoline ring, each of which may be unsubstituted or subsituted, and (B) WHEN T is the -CH2N3 group, then R is a substituted phenyl group AND THE NON-TOXIC, PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, PROCESSES FOR PREPARING THE SAME, AND ANTI-MICROBIAL COMPOSITIONS CONTAINING THE SAME. |
