发明名称 |
Steroid total synthesis process utilizing asymmetric induction |
摘要 |
A multi-step, stereospecific total synthesis of steroids is disclosed. The starting materials for this process are the relatively inexpensive and readily available m-alkoxy acetophenones. The process is suitable for the preparation of racemic or optically active, medicinally valuable steroids, particularly A-ring aromatic steroids. This process features an early optical resolution and a unique asymmetric induction which insures the correct stereochemistry of the final steroidal product.
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申请公布号 |
US4102925(A) |
申请公布日期 |
1978.07.25 |
申请号 |
US19760753340 |
申请日期 |
1976.12.22 |
申请人 |
HOFFMANN-LA ROCHE INC. |
发明人 |
COHEN, NOAL;SAUCY, GABRIEL |
分类号 |
C07C49/255;C07C59/90;C07D307/33;(IPC1-7):C07C91/18 |
主分类号 |
C07C49/255 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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