摘要 |
<p>Hexahydro-benzocyclononenes of formula (I): (where X is O and R' and R2 are different; R' being OH and R2 being 1-6C alkoxy; 7-9C aralkoxy; amino carrying a 1-6 C alkyl, 3-6C cycloalkyl or 7-9C aralkyl residue; or hydrazino opt. substd. by aryl, or R' and R2 are identical, and are amino groups carrying a 1-6C alkyl, 3-6C cycloalkyl or 7-9C aralkyl residue; amino groups derived from a 5- to 7-membered secondary cyclic amine; or hydrazino opt. subst. by aryl; or X is imino and R' and R2 are each OH). (I) have anticonvulsant, sedative, analgesic or anti-inflammatory activity. (I; X= O, R'=R2=pyrrolidino) also has hypertensive activity.</p> |