Para-nitro-phenetole prepn. - from para-chloro-nitrobenzene and ethanol in di:methyl sulphoxide

摘要

Pren. of p-nitrophenetole (I) comprises reacting p-chloronitrobenzene (II) with EtOH in DMSO in the presence of an alkali metal hydroxide. (I) can be reduced to p-phenetidine, a dyestuffs intermediate. Carrying out the reaction in DMSO ensures high yields (e.g. 93-97%) and gives a high-purity product free of traces of (II).