摘要 |
New process for the preparation of trans- DELTA 2-prostaglandins of the formula (WHEREIN A represents a grouping of the PGE, PGF or PGA type, X represents -CH2CH2- or trans -CH=CH-, R1 represents an alkyl radical of 1 to 10 carbon atoms or an alkyl radical of 1 to 6 carbon atoms carrying a phenyl substituent or a cycloalkyl substituent of 5 to 7 carbon atoms, R2 represents a hydrogen atom or an alkyl radical of 1 to 4 carbon atoms) and alkyl esters thereof having 1 to 10 carbon atoms in the chain, which comprises reacting a cyclopentane derivative of the formula: |