Antibiotics AM 31 alpha, beta and gamma and diamino alditol derivs. - effective against Escherichia coli, Salmonella typhosa and Klebsiella pneumoniae by culture of streptoverticillium netropis NRRL 5774

摘要

Diaminoalditol derivs. (I) and diaminoalditol (II) and their acid addition salts are novel cpds. (where R = H or 1-12C alkanoyl). (I) are antibiotics active against gram-positive and gram-negative bacteria when administered parenterally e.g. in vivo activity in mice shows them to be effect against Escherichia coli, Salmonella typhosa and Klebsiella pneumoniae. MIC tests against a wide range of organisms are described.