AN RHEUMATISCHER ARTHRITIS BETEILIGTE GENOMISCHE DNAS, DIAGNOSEVERFAHREN DAFÜR, VERFAHREN ZUR BEURTEILUNG DER AUSBRUCHSGEFAHR DAVON UND DIAGNOSTISCHER KIT ZUM NACHWEIS DAVON

摘要

A genomic DNA involved in rheumatoid arthritis, a method of diagnosing rheumatoid arthritis or a method of judging onset risk of rheumatoid arthritis, and a diagnostic kit for diagnosing rheumatoid arthritis or judging onset risk of rheumatoid arthritis, which genomic DNA comprises at least one of the following mutations in genomic DNA consisting of the base sequence of SEQ ID NO: 1: (1) substitution of thymine (t) for cytosine (c) at the position-1987; (2) substitution of guanine (g) for thymine (t) at the position-3664; and (3) substitution of cytosine (c) for adenine (a) at the position-3769.