VERFAHREN ZUR HERSTELLUNG EINES DIAGNOSTISCHEN MITTELS ZUR KONTROLLE DER GERINNUNGSFAHIGKEIT DES BLUTES

摘要

A diagnostic agent containing thromboplastin sensitive to factor VII and factor X for measuring the coagulability of blood is prepared by extracting an aqueous suspension of thrombogenic tissue at pH 10 to 12, acidifying the extract, separating the extract from the tissue and adding a water-soluble calcium salt to the extract. The agent can be stabilized by adding to the extract cholanic acid and a water-soluble heavy metal-II-salt.