摘要 |
<p>Amines of the formula WHEREIN R1 is lower alkyl, lower alkoxy or amino, R2 is hydrogen or lower alkyl, R3 is hydrogen, lower alkyl, carboxyl or lower alkoxycarbonyl, R4 is hydrogen or lower alkyl, R5 is lower alkyl, aryl-lower alkyl or optionally functionally modified carboxy-lower alkyl and R6 denotes halogen, trifluoromethyl, lower alkyl, lower alkenyl, lower alkoxy, lower alkenyloxy, nitro, lower alkoxymethyl, carbamoyl, N-lower alkylcarbamoyl, nitrile, lower alkinyloxy or hydrogen, and their salts block cardiac and vascular beta -receptors the are useful in the treatment of arrhythenias and angina pectoris and as intermediates for, especially for pharmaceutically active substances.</p> |